This Tribal Health Governance Transformation Resource is a practical guide to enhance tribal governance and public health law, build strategic partnerships, and improve community health. This resource draws upon Indigenous models of nation building and healing to promote cultural and political sovereignty, and redefine and strengthen governance for health. The Nation Building Principles woven throughout this resource are based on decades of research conducted by the Harvard Project on American Indian Economic Development, and its partner organization, the Native Nations Institute for Leadership, Management and Policy at the University of Arizona, Udall Center for Studies in Public Policy. The second model, Becoming Butterfly, was inspired by the Community Involvement to Renew Commitment, Leadership, and Effectiveness process for capacity development, which proposes a community-centered, public health approach to transform Indigenous health systems. Elements of both models have been integrated throughout the resource as a way of honoring the importance of direct experience, interconnectedness, and relationship, while accounting for the misalignment of values that often lies at the interface between tribal systems and local, state, and federal health systems.